microRNAs as therapeutic targets in intestinal diseases
نویسندگان
چکیده
منابع مشابه
MicroRNAs -the Next Generation Therapeutic Targets in Human Diseases
MicroRNAs (miRNAs), an abundant class of ~22-nucleotide non-coding RNAs, regulate the expression of genes at post transcriptional level. MiRNAs are important regulators of eukaryotic gene expression and therefore implicated in a wide range of biological processes. The miRNA-related genetic alterations are possibly more implicated human diseases than currently appreciated. Genetic variants in mi...
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Integrins are a large family of transmembrane heterodimeric proteins that constitute the main receptors for extracellular matrix components. Integrins were initially thought to be primarily involved in the maintenance of cell adhesion and tissue integrity. However, it is now appreciated that integrins play important roles in many other biological processes such as cell survival, proliferation, ...
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ژورنال
عنوان ژورنال: ExRNA
سال: 2019
ISSN: 2398-0060
DOI: 10.1186/s41544-019-0026-9